Package schrodinger :: Package application :: Package msv :: Package domain :: Module undoable_alignment :: Class ProteinAlignment

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Class ProteinAlignment

       object --+                    
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sip.simplewrapper --+                
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          sip.wrapper --+            
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     PyQt4.QtCore.QObject --+        
                            |        
      alignment.BaseAlignment --+    
                                |    
       alignment.ProteinAlignment --+
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                                   ProteinAlignment

A ProteinAlignment class that presents the same interface as a regular ProteinAlignment but optionally accomplishes mutating operations via a command stack.

If no command stack is set on the object, commands are executed but cannot be undone.

Instance Methods

[hide private]

setUndoStack(self, undo_stack)

addSeqs(self, seqs, index=None)
Add multiple sequences to the alignment

removeSeq(self, seq)
Remove a sequence from the alignment

removeSeqByIndex(self, index)
Remove a Sequence from the alignment

replaceSeq(self, seq, index)
Replace the sequence at the specified index with the elements in the specified sequence

addOrReplaceSeqs(self, seqs, identifier_func)
Given seqs and an identifier_func, replaces seqs in the alignment matching the identifier_func and appends any additional seqs to the alignment

removeAllSeqs(self)
Clears the entire alignment of sequences

removeResidues(self, residues)
Removes the specified residues from the alignment and emits the residuesRemoved signal with the selection

mutateResidues(self, mutations)
Mutate the residues at the specified locations in the alignment

addResidues(self, selection)
Adds the specified residues to the alignment

addGaps(self, gap_indices)
Adds gaps to the alignment

setGaps(self, gap_indices)
Sets gaps on the alignment

removeGaps(self, gap_indices)

removeTerminalGaps(self)
Removes the gaps from the ends of every sequence in the alignment

removeAllGaps(self)
Removes all the gaps of the sequences in the alignment.

_getInsertCommand(self, aln, start)

insertSubalignment(self, aln, start)
Insert an alignment into the current alignment at the specified index

removeSubalignment(self, start, end)
Remove a block of the subalignment from the start to end points, including column locks in that region

appendSubalignment(self, aln)
Append an alignment to this one

replaceSubalignment(self, aln, start, end)
Replace a subsection of the alignment indicated by start and end indices with the specified alignment

setLockedColumns(self, columns, lock=True)
Sets the specified columns to the specified lock state

setAllLocks(self, lock=True)
Convenience method to set all the locks to the specified lock state at once

minimizeAlignment(self)
Minimizes the alignment, i.e.

Inherited from alignment.ProteinAlignment: __init__

Inherited from alignment.BaseAlignment: __add__, __contains__, __deepcopy__, __getitem__, __iter__, __len__, __repr__, __str__, addSeq, alignmentLocked, calculateMatrix, columns, createConsensusSequence, findPattern, getAlignedBlocks, getColumn, getEntropy, getFrequencies, getGapIndicesByKeyFunc, getGaps, getGapsByKeyFunc, getGlobalAnnotationData, getIdentities, getRedundantSequences, getResidueData, getResidueIndices, getSeqIndex, getSimilarityScore, getSubalignment, getTerminalGaps, iterResidues, lockedColumns, makeResidueSelection, notifyResidueSelection, removeSeqs, replaceResiduesWithGaps

Inherited from alignment.BaseAlignment (private): _adjustGapsInSubalignments, _checkAlignmentLength, _getAddOrReplaceSeqs, _getAlignmentDescription, _getGapOnlyColumns, _getRegions, _getTextFormattedAlignment, _monitorSequence, _recalculateLength, _removeResidues, _sequenceLengthAboutToChange, _sequenceLengthChanged, _setLockedColumns, _stopMonitoringSequence, _validateGapIndices

Inherited from PyQt4.QtCore.QObject: __getattr__, blockSignals, childEvent, children, connect, connectNotify, customEvent, deleteLater, destroyed, disconnect, disconnectNotify, dumpObjectInfo, dumpObjectTree, dynamicPropertyNames, emit, event, eventFilter, findChild, findChildren, inherits, installEventFilter, isWidgetType, killTimer, metaObject, moveToThread, objectName, parent, property, pyqtConfigure, receivers, removeEventFilter, sender, senderSignalIndex, setObjectName, setParent, setProperty, signalsBlocked, startTimer, thread, timerEvent, tr, trUtf8

Inherited from sip.simplewrapper: __new__

Inherited from object: __delattr__, __format__, __getattribute__, __hash__, __reduce__, __reduce_ex__, __setattr__, __sizeof__, __subclasshook__

Class Methods

[hide private]

Inherited from alignment.BaseAlignment: mergePairwiseAlignments, padAlignment

Inherited from alignment.BaseAlignment (private): _insertGaps

Class Variables

[hide private]

Inherited from PyQt4.QtCore.QObject: staticMetaObject

Instance Variables

[hide private]

Inherited from alignment.BaseAlignment: alignmentLengthAboutToChange, alignmentLengthChanged, residuesAdded, residuesRemoved, residuesSelected, sequenceNameChanged, sequenceResiduesChanged, sequencesAboutToBeInserted, sequencesAboutToBeRemoved, sequencesInserted, sequencesRemoved

Properties

[hide private]

Inherited from alignment.ProteinAlignment: global_annotations, seq_annotations

Inherited from alignment.BaseAlignment: all_annotations

Inherited from object: __class__

Method Details

[hide private]

setUndoStack(self, undo_stack)

Parameters:

undo_stack (PyQt4.QtGui.QUndoStack Set the undo stack on the object) - The undo stack on which to push commands

addSeqs(self, seqs, index=None)

Add multiple sequences to the alignment

Parameters:

sequences - Sequences to add
start - The index at which to insert; if None, seq is appended

Decorators:

@command.do_command

Overrides: alignment.BaseAlignment.addSeqs

(inherited documentation)

removeSeq(self, seq)

Remove a sequence from the alignment

Parameters:

seq - The sequence to remove

Decorators:

@command.do_command

Overrides: alignment.BaseAlignment.removeSeq

(inherited documentation)

removeSeqByIndex(self, index)

Remove a Sequence from the alignment

Parameters:

index - The index of the sequence to remove

Decorators:

@command.do_command

Overrides: alignment.BaseAlignment.removeSeqByIndex

(inherited documentation)

replaceSeq(self, seq, index)

Replace the sequence at the specified index with the elements in the specified sequence

Note that this leaves the original sequence itself intact so that it continues to be monitored

Parameters:

seq - The sequence whose elements we use
index - The index of the sequence to replace

Decorators:

@command.do_command

Overrides: alignment.BaseAlignment.replaceSeq

(inherited documentation)

addOrReplaceSeqs(self, seqs, identifier_func)

Given seqs and an identifier_func, replaces seqs in the alignment matching the identifier_func and appends any additional seqs to the alignment

Parameters:

seqs - The sequences to add to the alignment
identifier_func - A key function to uniquely identify sequences

Decorators:

@command.do_command

Overrides: alignment.BaseAlignment.addOrReplaceSeqs

(inherited documentation)

removeAllSeqs(self)

Clears the entire alignment of sequences

Decorators:

@command.do_command

Overrides: alignment.BaseAlignment.removeAllSeqs

(inherited documentation)

removeResidues(self, residues)

Removes the specified residues from the alignment and emits the residuesRemoved signal with the selection

Parameters:

residues - The residues to remove

Decorators:

@command.do_command

Overrides: alignment.BaseAlignment.removeResidues

(inherited documentation)

mutateResidues(self, mutations)

Mutate the residues at the specified locations in the alignment

Note that the individual sequences will emit a signal announcing the mutation

Parameters:

mutations

Decorators:

@command.do_command

Overrides: alignment.BaseAlignment.mutateResidues

(inherited documentation)

addResidues(self, selection)

Adds the specified residues to the alignment

Parameters:

selection - A selection of residues

Decorators:

@command.do_command

Overrides: alignment.BaseAlignment.addResidues

(inherited documentation)

addGaps(self, gap_indices)

Adds gaps to the alignment

Parameters:

gap_indices - A list of lists of gap indices, one for each sequence in the alignment.
Note that the length of the gap_indices list must match the number of sequences in the alignment.

Decorators:

@command.do_command

Overrides: alignment.BaseAlignment.addGaps

(inherited documentation)

setGaps(self, gap_indices)

Sets gaps on the alignment

Parameters:

gap_indices - A list of lists of gap indices, one for each sequence in the alignment.

Decorators:

@command.do_command

Overrides: alignment.BaseAlignment.setGaps

(inherited documentation)

removeGaps(self, gap_indices)

Parameters:

gap_indices - Indices of gaps to remove

Decorators:

@command.do_command

Overrides: alignment.BaseAlignment.removeGaps

(inherited documentation)

removeTerminalGaps(self)

Removes the gaps from the ends of every sequence in the alignment

Decorators:

@command.do_command

Overrides: alignment.BaseAlignment.removeTerminalGaps

(inherited documentation)

removeAllGaps(self)

Removes all the gaps of the sequences in the alignment. This also unlocks all columns

Decorators:

@command.do_command

Overrides: alignment.BaseAlignment.removeAllGaps

(inherited documentation)

insertSubalignment(self, aln, start)

Insert an alignment into the current alignment at the specified index

Parameters:

aln - The alignment to insert
start - The index at which to insert the alignment

Decorators:

@command.do_command

Overrides: alignment.BaseAlignment.insertSubalignment

(inherited documentation)

removeSubalignment(self, start, end)

Remove a block of the subalignment from the start to end points, including column locks in that region

Parameters:

start - The start index of the columns to remove
end - The end index of the columns to remove

Decorators:

@command.do_command

Overrides: alignment.BaseAlignment.removeSubalignment

(inherited documentation)

appendSubalignment(self, aln)

Append an alignment to this one

Parameters:

aln - The alignment to append

Decorators:

@command.do_command

Overrides: alignment.BaseAlignment.appendSubalignment

(inherited documentation)

replaceSubalignment(self, aln, start, end)

Replace a subsection of the alignment indicated by start and end indices with the specified alignment

Parameters:

aln - The alignment to insert
start - The index at which to insert the alignment

Decorators:

@command.do_command

Overrides: alignment.BaseAlignment.replaceSubalignment

(inherited documentation)

setLockedColumns(self, columns, lock=True)

Sets the specified columns to the specified lock state

In undoable subclasses, this is an undoable method. We offer a private version of the method so that other undoable methods can call it without calling a second undoable method.

Parameters:

columns - an iterable of columns to set, specified by index
lock - Whether to lock or unlock columns
reset - Whether to reset the locks or add to existing ones

Decorators:

@command.do_command

Overrides: alignment.BaseAlignment.setLockedColumns

(inherited documentation)

setAllLocks(self, lock=True)

Convenience method to set all the locks to the specified lock state at once

Parameters:

lock - Whether to lock or unlock the specified columns

Decorators:

@command.do_command

Overrides: alignment.BaseAlignment.setAllLocks

(inherited documentation)

minimizeAlignment(self)

Minimizes the alignment, i.e. removes all gaps from the gap-only columns.

Decorators:

@command.do_command

Overrides: alignment.BaseAlignment.minimizeAlignment

(inherited documentation)